Pickens County Vacations & Trips from $750

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Your Pickens County Vacation

Make planning your next big adventure quick and easy with a Pickens County vacation package. Whether it's the cuisine, nature or something else that draws you to this destination, our packages will help you experience it all. Start your trip to Pickens County with a couple of days in Clemson visiting popular sights like Memorial Stadium and South Carolina Botanical Gardens. Powdersville is another top city that lures travelers from near and far. Falls Park on the Reedy and Bon Secours Wellness Arena are two of the top places to see here. Expedia has hotels, flights, car rentals and more to help you create your own customized Pickens County vacation today.

Top destinations in Pickens County

An aerial view of a university campus with multiple buildings, green spaces, and a prominent clock tower.

Clemson

Clemson
A lake surrounded by forested hills.

Easley

Easley
A mountain range with a sunset.

Sunset

Sunset
A dry grassland with a few trees, a red building, and mountains in the background.

Pickens

Pickens
A waterfall cascading over a rocky ledge into a calm river surrounded by lush greenery.

Central

Central

The Latest Pickens County Vacation Packages

Price found within the past 48 hours. Click for updated prices.
AutoCamp Asheville

AutoCamp Asheville

$750
per person
Nov 11 - Nov 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
9.6/10 Exceptional! (11 reviews)
For someone who doesn't normally embrace the camping lifestyle, I was pleasantly surprised with the experience. The staff was super helpful, the riverside location was beautiful and the amenities were a nice upgraded touch. Next time I will be more prepared to enjoy the campfire and river to the fullest extent

Reviewed on Sep 8, 2026

14k sq ft Mountaintop Estate - Private Golf Course

14k sq ft Mountaintop Estate - Private Golf Course

Save 100% on your flight
$8,811
per person
Nov 11 - Nov 16
found 4 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
No reviews
Leyland by Avantstay Cabin Mansion w/ Views

Leyland by Avantstay Cabin Mansion w/ Views

Beaverdam Valley
Save 100% on your flight
$2,927
per person
Nov 11 - Nov 16
just found
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
No reviews
Scenic 4BR w Deck Farm Views Free Tix

Scenic 4BR w Deck Farm Views Free Tix

Save 100% on your flight
$3,710
per person
Nov 11 - Nov 16
just found
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
No reviews
The Restoration Asheville

The Restoration Asheville

Downtown Asheville
$890
per person
Nov 12 - Nov 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
9.8/10 Exceptional! (1,214 reviews)
The homeless population around the hotel was frightening and sad. I did not feel safe . It was noisy. There was a lot of drug use all around as well. The hotel staff needs training and organization.

Reviewed on Sep 10, 2026

Find the Best Pickens County Vacation Packages

Pickens County Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Greenville-Spartanburg Intl. Airport (GSP)
Population
3,200
Top Sights
South Carolina Botanical Gardens, Keowee-Toxaway State Park and Larry W. Abernathy Waterfront Park

Pickens County Hotel Deals

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$101 nightly
$112 total
Sep 14 - Sep 15
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center
Inn @ Clemson

Inn @ Clemson

1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$87 nightly
$97 total
Sep 14 - Sep 15
Total with taxes and fees
Inn @ Clemson
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

110 Sloan St Clemson SC
$239 nightly
$265 total
Sep 27 - Sep 28
Total with taxes and fees
9.8/10 Exceptional! (886 reviews)
"Absolutely perfect in every way!"

Reviewed on Sep 7, 2026

The Shepherd Hotel Downtown Clemson
See all 5,266 properties in Pickens County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Pickens County attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
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A mountainous landscape with a lake and a prominent cliff.

Table Rock State Park

9.2/10 (159 reviews)
You can take time to visit Table Rock State Park during your travels to Pickens. Wander the riverfront or discover the waterfalls in this family-friendly area.
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A white flower with a yellow center surrounded by green leaves.

South Carolina Botanical Gardens

9.2/10 (133 reviews)
Explore the great outdoors at South Carolina Botanical Gardens, a lovely green space in Clemson. You can attend a sporting event while in the area.
See properties
Two people walking on a grassy hill with a mountain in the background.

Walker Golf Course

9.2/10 (76 reviews)
Enjoy a round of golf in Clemson at Walker Golf Course. Amble around the area's lakeside or attend a football game.
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Memorial Stadium

9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
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Southern Wesleyan University

10.0/10 (2 reviews)
Enjoy the collegiate vibe when you visit Southern Wesleyan University, during your travels in Central. You can attend a sporting event while in the area.
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J.B. Red Owens Sports Complex

8.2/10 (12 reviews)
Catch an event at J.B. Red Owens Sports Complex during your trip to Easley. Stroll along the area's riverfront, or simply savor its top-notch restaurants.
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Littlejohn Coliseum

9.4/10 (141 reviews)
Catch an event at Littlejohn Coliseum during your trip to Clemson. Amble around the area's lakeside or attend a football game.
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What to do in Pickens County

Spooky & Haunted Paranormal Bar Crawl Downtown Greenville

Greenville Haunted Bar Tour

$28
per adult
100% of travellers recommend
Greenville Haunted Bar Tour
Just Desserts Tour In Greenville

Just Desserts Tour In Greenville

$95
per adult
Just Desserts Tour In Greenville
Saturday Evening Craft Cocktail Tour

Saturday Evening Craft Cocktail Tour

$105
per adult
100% of travellers recommend
Saturday Evening Craft Cocktail Tour
See all activities in Pickens County
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.